FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growt...
FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Netrin-1 is an essential extracellular chemoattractant that signals through its receptor DCC to guide commissural axon extension in the embryonic spinal cord. DCC directs the organization of F-actin in growth cones by activating an intracellular protein complex that includes the Rho GTPase Cdc42, a critical regulator of cell polarity and directiona...
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FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones
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TN_cdi_plos_journals_1808344072
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1808344072
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0159405
