HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3
HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Chromatin remodelling is essential for cardiac development. Interestingly, the role of histone chaperones has not been investigated in this regard. HIRA is a member of the HUCA (HIRA/UBN1/CABIN1/ASF1a) complex that deposits the variant histone H3.3 on chromatin independently of replication. Lack of HIRA has general effects on chromatin and gene exp...
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Full title
HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3
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TN_cdi_plos_journals_1812542191
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1812542191
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0161096
