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Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably...

Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1813899603

Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

About this item

Full title

Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-08, Vol.11 (8), p.e0161450-e0161450

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The voltage dependent sodium channel Nav1.9, is expressed preferentially in peripheral sensory neurons and has been linked to human genetic pain disorders, which makes it target of interest for the development of new pain therapeutics. However, characterization of Nav1.9 pharmacology has been limited due in part to the historical difficulty of func...

Alternative Titles

Full title

Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1813899603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1813899603

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0161450

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