Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells
Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The Suppressors of Cytokine Signalling (SOCS) proteins are negative regulators of cytokine signalling required to prevent excess cellular responses. SOCS1 and SOCS3 are essential to prevent inflammatory disease, SOCS1 by attenuating responses to IFNγ and gamma-common (γc) cytokines, and SOCS3 via regulation of G-CSF and IL-6 signalling. SOCS1 and S...
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Full title
Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells
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TN_cdi_plos_journals_1815978559
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1815978559
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0162111
