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Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signalin...

Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signalin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1816053488

Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries

About this item

Full title

Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-09, Vol.11 (9), p.e0162029-e0162029

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The sphingosine-1-phosphate (S1P) analog FTY720 exerts pleiotropic effects on the cardiovascular system and causes down-regulation of S1P receptors. Myogenic constriction is an important mechanism regulating resistance vessel function and is known to be modulated by S1P. Here we investigated myogenic constriction and vascular function of mesenteric...

Alternative Titles

Full title

Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1816053488

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1816053488

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0162029

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