The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Dengue virus NS5 protein plays multiple functions in the cytoplasm of infected cells, enabling viral RNA replication and counteracting host antiviral responses. Here, we demonstrate a novel function of NS5 in the nucleus where it interferes with cellular splicing. Using global proteomic analysis of infected cells together with functional studies, w...
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Full title
The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
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Record Identifier
TN_cdi_plos_journals_1820282432
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1820282432
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005841
