Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection
Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection
About this item
Full title
Author / Creator
Demers, Korey R , Makedonas, George , Buggert, Marcus , Eller, Michael A , Ratcliffe, Sarah J , Goonetilleke, Nilu , Li, Chris K , Eller, Leigh Anne , Rono, Kathleen , Maganga, Lucas , Nitayaphan, Sorachai , Kibuuka, Hannah , Routy, Jean-Pierre , Slifka, Mark K , Haynes, Barton F , McMichael, Andrew J , Bernard, Nicole F , Robb, Merlin L and Betts, Michael R
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The loss of HIV-specific CD8+ T cell cytolytic function is a primary factor underlying progressive HIV infection, but whether HIV-specific CD8+ T cells initially possess cytolytic effector capacity, and when and why this may be lost during infection, is unclear. Here, we assessed CD8+ T cell functional evolution from primary to chronic HIV infectio...
Alternative Titles
Full title
Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection
Authors, Artists and Contributors
Author / Creator
Makedonas, George
Buggert, Marcus
Eller, Michael A
Ratcliffe, Sarah J
Goonetilleke, Nilu
Li, Chris K
Eller, Leigh Anne
Rono, Kathleen
Maganga, Lucas
Nitayaphan, Sorachai
Kibuuka, Hannah
Routy, Jean-Pierre
Slifka, Mark K
Haynes, Barton F
McMichael, Andrew J
Bernard, Nicole F
Robb, Merlin L
Betts, Michael R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1820282592
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1820282592
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005805
