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The Effect of Albumin on MRP2 and BCRP in the Vesicular Transport Assay

The Effect of Albumin on MRP2 and BCRP in the Vesicular Transport Assay

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1826186704

The Effect of Albumin on MRP2 and BCRP in the Vesicular Transport Assay

About this item

Full title

The Effect of Albumin on MRP2 and BCRP in the Vesicular Transport Assay

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-10, Vol.11 (10), p.e0163886-e0163886

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The ABC transporters multidrug resistance associated protein 2 (MRP2) and breast cancer resistance protein (BCRP) are of interest in drug development, since they affect the pharmacokinetics of several drugs. Membrane vesicle transport assays are widely used to study interactions with these proteins. Since albumin has been found to affect the kineti...

Alternative Titles

Full title

The Effect of Albumin on MRP2 and BCRP in the Vesicular Transport Assay

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1826186704

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1826186704

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0163886

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