Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression
Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Cardiovascular diseases are risk factors for depression in humans. We recently proposed that σ1 receptor (σ1R) stimulation rescued cardiac hypertrophy and heart failure induced by transverse aortic constriction (TAC) in mice. Importantly, σ1R stimulation reportedly ameliorates depression-like behaviors in rodents. Thus, we hypothesized that impaire...
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Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression
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TN_cdi_plos_journals_1829040693
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829040693
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0163992
