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Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829040822

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties

About this item

Full title

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-10, Vol.11 (10), p.e0164695-e0164695

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Argonaute (Ago) proteins from all three domains of life are key players in processes that specifically regulate cellular nucleic acid levels. Some of these Ago proteins, among them human Argonaute2 (hAgo2) and Ago from the archaeal organism Methanocaldococcus jannaschii (MjAgo), are able to cleave nucleic acid target strands that are recognised via...

Alternative Titles

Full title

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1829040822

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829040822

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0164695

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