Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties
Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Argonaute (Ago) proteins from all three domains of life are key players in processes that specifically regulate cellular nucleic acid levels. Some of these Ago proteins, among them human Argonaute2 (hAgo2) and Ago from the archaeal organism Methanocaldococcus jannaschii (MjAgo), are able to cleave nucleic acid target strands that are recognised via...
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Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties
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TN_cdi_plos_journals_1829040822
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829040822
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0164695