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Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829444220

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

About this item

Full title

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2016-09, Vol.14 (9), p.e1002558-e1002558

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cognitive defects in autism spectrum disorder (ASD) include socialization and communication: key behavioral capacities that separate humans from other species. Here, we analyze gene expression in the prefrontal cortex of 63 autism patients and control individuals, as well as 62 chimpanzees and macaques, from natal to adult age. We show that among a...

Alternative Titles

Full title

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1829444220

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829444220

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1002558

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