MUC1-ARF—A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Fram...
MUC1-ARF—A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein highly expressed in human malignancies. Here we show that an AUG codon downstream to the MUC1-TM initiation codon initiates...
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MUC1-ARF—A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA
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TN_cdi_plos_journals_1830874609
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1830874609
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0165031
