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Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1834883923

Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

About this item

Full title

Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-11, Vol.11 (11), p.e0165922-e0165922

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Anti-bone resorptive drugs such as bisphosphonates, the anti-RANKL antibody (denosumab), or selective estrogen receptor modulators (SERMs) have been developed to treat osteoporosis. Mechanisms underlying activity of bisphosphonates or denosumab in this context are understood, while it is less clear how SERMs like tamoxifen, raloxifene, or bazedoxif...

Alternative Titles

Full title

Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1834883923

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1834883923

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0165922

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