Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Ret...
Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study
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United States: Public Library of Science
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English
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United States: Public Library of Science
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A large isoniazid-resistant tuberculosis outbreak centred on London, United Kingdom, has been ongoing since 1995. The aim of this study was to investigate the power and value of whole genome sequencing (WGS) to resolve the transmission network compared to current molecular strain typing approaches, including analysis of intra-host diversity within...
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Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study
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TN_cdi_plos_journals_1840921542
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1840921542
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1549-1676,1549-1277
E-ISSN
1549-1676
DOI
10.1371/journal.pmed.1002137