A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses
A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Humans express seven human APOBEC3 proteins, which can inhibit viruses and endogenous retroelements through cytidine deaminase activity. The seven paralogs differ in the potency of their antiviral effects, as well as in their antiviral targets. One APOBEC3, APOBEC3C, is exceptional as it has been found to only weakly block viruses and endogenous re...
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Full title
A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses
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TN_cdi_plos_journals_1840926022
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1840926022
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005865
