No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication...
No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
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Author / Creator
Johnson, Emma C. , Bjelland, Douglas W. , Howrigan, Daniel P. , Abdellaoui, Abdel , Breen, Gerome , Borglum, Anders , Cichon, Sven , Degenhardt, Franziska , Forstner, Andreas J. , Frank, Josef , Genovese, Giulio , Heilmann-Heimbach, Stefanie , Herms, Stefan , Hoffman, Per , Maier, Wolfgang , Mattheisen, Manuel , Morris, Derek , Mowry, Bryan , Müller-Mhysok, Betram , Neale, Benjamin , Nenadic, Igor , Nöthen, Markus M. , O’Dushlaine, Colm , Rietschel, Marcella , Ruderfer, Douglas M. , Rujescu, Dan , Schulze, Thomas G. , Simonson, Matthew A. , Stahl, Eli , Strohmaier, Jana , Witt, Stephanie H. , Sullivan, Patrick F. , Keller, Matthew C. and Schizophrenia Working Group of the Psychiatric Genomics Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
It is well known that inbreeding increases the risk of recessive monogenic diseases, but it is less certain whether it contributes to the etiology of complex diseases such as schizophrenia. One way to estimate the effects of inbreeding is to examine the association between disease diagnosis and genome-wide autozygosity estimated using runs of homoz...
Alternative Titles
Full title
No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
Authors, Artists and Contributors
Author / Creator
Bjelland, Douglas W.
Howrigan, Daniel P.
Abdellaoui, Abdel
Breen, Gerome
Borglum, Anders
Cichon, Sven
Degenhardt, Franziska
Forstner, Andreas J.
Frank, Josef
Genovese, Giulio
Heilmann-Heimbach, Stefanie
Herms, Stefan
Hoffman, Per
Maier, Wolfgang
Mattheisen, Manuel
Morris, Derek
Mowry, Bryan
Müller-Mhysok, Betram
Neale, Benjamin
Nenadic, Igor
Nöthen, Markus M.
O’Dushlaine, Colm
Rietschel, Marcella
Ruderfer, Douglas M.
Rujescu, Dan
Schulze, Thomas G.
Simonson, Matthew A.
Stahl, Eli
Strohmaier, Jana
Witt, Stephanie H.
Sullivan, Patrick F.
Keller, Matthew C.
Schizophrenia Working Group of the Psychiatric Genomics Consortium
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1840927988
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1840927988
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1006343
