Algorithm Optimization in Methylation Detection with Multiple RT-qPCR
Algorithm Optimization in Methylation Detection with Multiple RT-qPCR
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Author / Creator
Song, Lele , Li, Yuemin , Jia, Jia , Zhou, Guangpeng , Wang, Jianming , Kang, Qian , Jin, Peng , Sheng, Jianqiu , Cai, Guoxiang , Cai, Sanjun and Han, Xiaoliang
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Epigenetic markers based on differential methylation of DNA sequences are used in cancer screening and diagnostics. Detection of abnormal methylation at specific loci by real-time quantitative polymerase chain reaction (RT-qPCR) has been developed to enable high-throughput cancer screening. For tests that combine the results of multiple PCR replica...
Alternative Titles
Full title
Algorithm Optimization in Methylation Detection with Multiple RT-qPCR
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Record Identifier
TN_cdi_plos_journals_1844595850
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1844595850
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0163333
