Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice
Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Endothelial-mesenchymal transition (EndMT) drives endothelium to contribute to normal development and disease processes. Here, we report that EndMTs occur in the diabetic endothelium of Ins2Akita/wt mouse, and show that induction of sex determining region Y-box 2 (Sox2) is a mediator of excess BMP signaling that results in activation of EndMTs and...
Alternative Titles
Full title
Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1847562506
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1847562506
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0167936
