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CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macr...

CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1849654534

CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

About this item

Full title

CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2016-11, Vol.10 (11), p.e0005089-e0005089

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1-/- mice upon Rickettsia typhi infection. Here, we show that CD4+ TH1 cells that are gene...

Alternative Titles

Full title

CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1849654534

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1849654534

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0005089

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