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Arginine and Lysine Transporters Are Essential for Trypanosoma brucei

Arginine and Lysine Transporters Are Essential for Trypanosoma brucei

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855060791

Arginine and Lysine Transporters Are Essential for Trypanosoma brucei

About this item

Full title

Arginine and Lysine Transporters Are Essential for Trypanosoma brucei

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-01, Vol.12 (1), p.e0168775-e0168775

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

For Trypanosoma brucei arginine and lysine are essential amino acids and therefore have to be imported from the host. Heterologous expression in Saccharomyces cerevisiae mutants identified cationic amino acid transporters among members of the T. brucei AAAP (amino acid/auxin permease) family. TbAAT5-3 showed high affinity arginine uptake (Km 3.6 ±...

Alternative Titles

Full title

Arginine and Lysine Transporters Are Essential for Trypanosoma brucei

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1855060791

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855060791

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0168775

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