Log in to save to my catalogue

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologi...

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855069443

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients

About this item

Full title

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-01, Vol.12 (1), p.e0168550

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

We previously reported improved pathologic complete response (pCR) in a prospective phase II study using neoadjuvant bevacizumab in combination with chemotherapy compared to chemotherapy alone in breast cancer patients (41% vs. 25%, p = 0.0291). In this study, we queried germline single-nucleotide polymorphisms (SNPs) in angiogenesis-related genes...

Alternative Titles

Full title

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1855069443

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855069443

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0168550

How to access this item