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Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures

Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855325594

Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures

About this item

Full title

Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-01, Vol.12 (1), p.e0169506-e0169506

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Differentiated neurons can be rapidly acquired, within days, by inducing stem cells to express neurogenic transcription factors. We developed a protocol to maintain long-term cultures of human neurons, called iNGNs, which are obtained by inducing Neurogenin-1 and Neurogenin-2 expression in induced pluripotent stem cells. We followed the functional...

Alternative Titles

Full title

Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1855325594

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855325594

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0169506

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