Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OL...
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Telomerase is expressed in early human development and then becomes silenced in most normal tissues. Because ~90% of primary human tumors express telomerase and generally maintain very short telomeres, telomerase is carefully regulated, particularly in large, long-lived mammals. In the current report, we provide substantial evidence for a new regul...
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Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer
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TN_cdi_plos_journals_1858865459
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1858865459
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1545-7885,1544-9173
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1545-7885
DOI
10.1371/journal.pbio.2000016
