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Progressive APOBEC3B mRNA expression in distant breast cancer metastases

Progressive APOBEC3B mRNA expression in distant breast cancer metastases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1863195674

Progressive APOBEC3B mRNA expression in distant breast cancer metastases

About this item

Full title

Progressive APOBEC3B mRNA expression in distant breast cancer metastases

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-01, Vol.12 (1), p.e0171343

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expression is associated with poor prognosis. However, its expressi...

Alternative Titles

Full title

Progressive APOBEC3B mRNA expression in distant breast cancer metastases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1863195674

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1863195674

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0171343

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