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In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formatio...

In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1863196750

In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation

About this item

Full title

In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-01, Vol.12 (1), p.e0170735-e0170735

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Like embryonic stem cells, induced pluripotent stem cells (iPSCs) can differentiate into all three germ layers in an in vitro system. Here, we developed a new technology for obtaining neural stem cells (NSCs) from iPSCs through chimera formation, in an in vivo environment. iPSCs contributed to the neural lineage in the chimera, which could be effic...

Alternative Titles

Full title

In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1863196750

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1863196750

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0170735

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