NOX1 and NOX4 are required for the differentiation of mouse F9 cells into extraembryonic endoderm
NOX1 and NOX4 are required for the differentiation of mouse F9 cells into extraembryonic endoderm
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Mouse F9 cells differentiate to primitive endoderm (PrE) when treated with retinoic acid (RA). Differentiation is accompanied by increased reactive oxygen species (ROS) levels, and while treating F9 cells with antioxidants attenuates differentiation, H2O2 treatment alone is sufficient to induce PrE. We identified the NADPH oxidase (NOX) complexes a...
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NOX1 and NOX4 are required for the differentiation of mouse F9 cells into extraembryonic endoderm
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TN_cdi_plos_journals_1864404927
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1864404927
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0170812
