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The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor O...

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor O...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1865236991

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

About this item

Full title

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2016-10, Vol.12 (10), p.e1005934-e1005934

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The origin recognition complex (ORC) coordinates a series of events that lead to initiation of DNA strand duplication. As a nuclear double stranded DNA plasmid, the papillomavirus (PV) genome resembles a mini-chromosome in infected cells. To initiate its replication, the viral E2 protein binds to and recruits the E1 DNA helicase at the viral origin...

Alternative Titles

Full title

The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1865236991

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1865236991

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1005934

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