Log in to save to my catalogue

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory d...

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1868285210

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome

About this item

Full title

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-02, Vol.12 (2), p.e0172116-e0172116

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A hallmark of acute respiratory distress syndrome (ARDS) is accumulation of protein-rich edema in the distal airspaces and its removal is critical for patient survival. Previous studies have shown a detrimental role of Glycogen Synthase Kinase (GSK) 3β during ARDS via inhibition of alveolar epithelial protein transport. We hypothesized that post-tr...

Alternative Titles

Full title

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1868285210

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1868285210

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0172116

How to access this item