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Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood...

Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1871526038

Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells)

About this item

Full title

Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells)

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-02, Vol.12 (2), p.e0172430-e0172430

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A human bone marrow-derived mesenchymal stromal cell (MSCs) and cord blood-derived CD34+ stem cell co-culture system was set up in order to evaluate the proliferative and differentiative effects induced by MSCs on CD34+ stem cells, and the reciprocal influences on gene expression profiles. After 10 days of co-culture, non-adherent (SN-fraction) and...

Alternative Titles

Full title

Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1871526038

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1871526038

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0172430

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