Novel CD28 antagonist mPEG PV1-Fab’ mitigates experimental autoimmune uveitis by suppressing CD4+ T...
Novel CD28 antagonist mPEG PV1-Fab’ mitigates experimental autoimmune uveitis by suppressing CD4+ T lymphocyte activation and IFN-γ production
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Autoimmune Uveitis is an important chronic inflammatory disease and a leading cause of impaired vision and blindness. This ocular autoimmune disorder is mainly mediated by T CD4+ lymphocytes poising a TH1 phenotype. Costimulatory molecules are known to play an important role on T cell activation and therefore represent interesting therapeutical tar...
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Full title
Novel CD28 antagonist mPEG PV1-Fab’ mitigates experimental autoimmune uveitis by suppressing CD4+ T lymphocyte activation and IFN-γ production
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TN_cdi_plos_journals_1873345316
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1873345316
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0171822
