Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanom...
Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Platelets modulate the process of cancer metastasis. However, current knowledge on the direct interaction of platelets and tumor cells is mostly based on findings obtained in vitro. We addressed the role of the platelet fibrinogen receptor glycoprotein IIb (integrin αIIb) for experimental melanoma metastasis in vivo. Highly metastatic B16-D5 melano...
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Full title
Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis
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TN_cdi_plos_journals_1873690756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1873690756
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0172788
