Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Polymorphic variants of the FTO (fat mass and obesity) gene associate with body mass index in humans, but the underlying molecular mechanisms have not been firmly determined. FTO is linked to energy homeostasis via amino acid sensing and is thought to activate the mammalian target of rapamycin complex 1, a negative regulator of autophagy. FTO local...
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Full title
Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
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TN_cdi_plos_journals_1876819123
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1876819123
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0168182
