ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13
ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13
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United States: Public Library of Science
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English
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United States: Public Library of Science
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ATP6V1H is a component of a large protein complex with vacuolar ATPase (V-ATPase) activity. We identified two generations of individuals in which short stature and osteoporosis co-segregated with a mutation in ATP6V1H. Since V-ATPases are highly conserved between human and zebrafish, we generated loss-of-function mutants in atp6v1h in zebrafish thr...
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ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13
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TN_cdi_plos_journals_1878070086
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1878070086
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1006481
