Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells
Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells
About this item
Full title
Author / Creator
Liu, Shiwei , Du, Fang , Li, Xin , Wang, Mingming , Duan, Ruixue , Zhang, Jiaxin , Wu, Yaru and Zhang, Qi
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
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Scope and Contents
Contents
Pancreatic β cell dysfunction and reduction due to glucose toxicity play a crucial role in the development of type 2 diabetes mellitus (T2DM). Irisin, a novel exercise-induced myokine, reduces obesity, improves insulin resistance and lowers blood glucose by promoting the browning of white adipose tissue, thereby enhancing thermogenesis and increasi...
Alternative Titles
Full title
Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_plos_journals_1886286802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1886286802
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0175498
