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Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters...

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1888656383

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

About this item

Full title

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2017-03, Vol.11 (3), p.e0005472

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate inhibits Leishmania growth and decreases its intrac...

Alternative Titles

Full title

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1888656383

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1888656383

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0005472

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