Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters...
Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate inhibits Leishmania growth and decreases its intrac...
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Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi
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TN_cdi_plos_journals_1888656383
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1888656383
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ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0005472