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Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and his...

Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and his...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1888947261

Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B

About this item

Full title

Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-04, Vol.12 (4), p.e0175792-e0175792

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The fusion (F) protein of RSV is the major vaccine target. This protein undergoes a conformational change from pre-fusion to post-fusion. Both conformations share antigenic sites II and IV. Pre-fusion F has unique antigenic sites p27, ø, α2α3β3β4, and MPE8; whereas, post-fusion F has unique antigenic site I. Our objective was to determine the antig...

Alternative Titles

Full title

Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1888947261

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1888947261

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0175792

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