Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administrat...
Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in cats.
Six healthy cats (4.9 ± 0.7 kg) were included in a prospective, randomized, blinded, crossover study. Simbadol™ (1.8 mg mL-1) was administered by the...
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Full title
Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats
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TN_cdi_plos_journals_1892318311
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1892318311
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0176443
