Log in to save to my catalogue

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin gener...

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin gener...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1895357587

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis

About this item

Full title

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-05, Vol.12 (5), p.e0177020-e0177020

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Impaired coagulation factor synthesis in cirrhosis causes a reduction of most pro- and anticoagulant factors. Cirrhosis patients show no clear bleeding or thrombotic phenotype, although they are at risk for both types of hemostatic event. Thrombin generation (TG) is a global coagulation test and its outcome depends on underlying pro- and anticoagul...

Alternative Titles

Full title

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1895357587

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1895357587

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0177020

How to access this item