Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imagin...
Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging
About this item
Full title
Author / Creator
Yang, Xiaoliang , Wang, Zihua , Xiang, Zhichu , Li, Dan , Hu, Zhiyuan , Cui, Wei , Geng, Lingling and Fang, Qiaojun
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
A high level of HER2 expression in breast cancer correlates with a higher tumor growth rate, high metastatic potential, and a poor long-term patient survival rate. Pertuzumab, a human monoclonal antibody, can reduce the effect of HER2 overexpression by preventing HER2 dimerization. In this study, a combination protocol of molecular dynamics modelin...
Alternative Titles
Full title
Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_1899336894
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1899336894
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1005441
