Complete mapping of viral escape from neutralizing antibodies
Complete mapping of viral escape from neutralizing antibodies
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Identifying viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a high-throughput approach to quantify the selection that monoclonal antibodies exert on all single amino-acid mutations to a viral protein. This approach, mutational antigenic profiling, involv...
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Full title
Complete mapping of viral escape from neutralizing antibodies
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TN_cdi_plos_journals_1900162913
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1900162913
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1006271