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Complete mapping of viral escape from neutralizing antibodies

Complete mapping of viral escape from neutralizing antibodies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1900162913

Complete mapping of viral escape from neutralizing antibodies

About this item

Full title

Complete mapping of viral escape from neutralizing antibodies

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2017-03, Vol.13 (3), p.e1006271-e1006271

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Identifying viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a high-throughput approach to quantify the selection that monoclonal antibodies exert on all single amino-acid mutations to a viral protein. This approach, mutational antigenic profiling, involv...

Alternative Titles

Full title

Complete mapping of viral escape from neutralizing antibodies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1900162913

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1900162913

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1006271

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