Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransfera...
Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase
About this item
Full title
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
To study the impact of epigenetic changes on biological functions, the ability to manipulate the epigenetic status of certain genomic regions artificially could be an indispensable technology. "Epigenome editing" techniques have gradually emerged that apply TALE or CRISPR/Cas9 technologies with various effector domains isolated from epigenetic code...
Alternative Titles
Full title
Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase
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Record Identifier
TN_cdi_plos_journals_1900214135
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1900214135
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0177764
