Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes oper...
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Adult male germline stem cells (spermatogonia) proliferate by mitosis and, after puberty, generate spermatocytes that undertake meiosis to produce haploid spermatozoa. Germ cells are under evolutionary constraint to curtail mutations and maintain genome integrity. Despite constant turnover, spermatogonia very rarely form tumors, so-called spermatoc...
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Full title
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline
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TN_cdi_plos_journals_1901358386
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1901358386
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0178169
