Role of LRRK2 in the regulation of dopamine receptor trafficking
Role of LRRK2 in the regulation of dopamine receptor trafficking
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Author / Creator
Rassu, Mauro , Del Giudice, Maria Grazia , Sanna, Simona , Taymans, Jean Marc , Morari, Michele , Brugnoli, Alberto , Frassineti, Martina , Masala, Alessandra , Esposito, Sonia , Galioto, Manuela , Valle, Cristiana , Carri, Maria Teresa , Biosa, Alice , Greggio, Elisa , Crosio, Claudia and Iaccarino, Ciro
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson's disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in the control of vesicle trafficking that in turn may regulate different aspects of neuronal physiology...
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Full title
Role of LRRK2 in the regulation of dopamine receptor trafficking
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TN_cdi_plos_journals_1906245514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1906245514
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0179082
