Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults
About this item
Full title
Author / Creator
Diemert, David J. , Freire, Janaína , Valente, Vanderson , Fraga, Carlos Geraldo , Talles, Frederico , Grahek, Shannon , Campbell, Doreen , Jariwala, Amar , Periago, Maria Victoria , Enk, Martin , Gazzinelli, Maria Flávia , Bottazzi, Maria Elena , Hamilton, Robert , Brelsford, Jill , Yakovleva, Anna , Li, Guangzhao , Peng, Jin , Correa-Oliveira, Rodrigo , Hotez, Peter and Bethony, Jeffrey
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Necator americanus Glutathione-S-Transferase-1 (Na-GST-1) plays a role in the digestion of host hemoglobin by adult N. americanus hookworms. Vaccination of laboratory animals with recombinant Na-GST-1 is associated with significant protection from challenge infection. Recombinant Na-GST-1 was expressed in Pichia pastoris and adsorbed to aluminum hy...
Alternative Titles
Full title
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults
Authors, Artists and Contributors
Author / Creator
Freire, Janaína
Valente, Vanderson
Fraga, Carlos Geraldo
Talles, Frederico
Grahek, Shannon
Campbell, Doreen
Jariwala, Amar
Periago, Maria Victoria
Enk, Martin
Gazzinelli, Maria Flávia
Bottazzi, Maria Elena
Hamilton, Robert
Brelsford, Jill
Yakovleva, Anna
Li, Guangzhao
Peng, Jin
Correa-Oliveira, Rodrigo
Hotez, Peter
Bethony, Jeffrey
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1910461703
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910461703
Other Identifiers
ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0005574
