Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell...
Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2
About this item
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) mediates viral entry into target cells. Cleavage and activation of SARS S by a host cell protease is essential for infectious viral entry and the responsible enzymes are potential targets for antiviral intervention. The type II transmembrane serine protease TMPRSS2 cl...
Alternative Titles
Full title
Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2
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Record Identifier
TN_cdi_plos_journals_1912161922
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1912161922
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0179177
