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Intratumoural production of TNFα by bacteria mediates cancer therapy

Intratumoural production of TNFα by bacteria mediates cancer therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1914835929

Intratumoural production of TNFα by bacteria mediates cancer therapy

About this item

Full title

Intratumoural production of TNFα by bacteria mediates cancer therapy

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-06, Vol.12 (6), p.e0180034-e0180034

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNFα) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is required in order to confine this toxicity within the locality of the tumour. Bacteria have a natural capacity to grow within tumours...

Alternative Titles

Full title

Intratumoural production of TNFα by bacteria mediates cancer therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1914835929

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1914835929

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0180034

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