Intratumoural production of TNFα by bacteria mediates cancer therapy
Intratumoural production of TNFα by bacteria mediates cancer therapy
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNFα) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is required in order to confine this toxicity within the locality of the tumour. Bacteria have a natural capacity to grow within tumours...
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Full title
Intratumoural production of TNFα by bacteria mediates cancer therapy
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TN_cdi_plos_journals_1914835929
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1914835929
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0180034