Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rat...
Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats
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Author / Creator
Bennion, Douglas M. , Isenberg, Jacob D. , Harmel, Allison T. , DeMars, Kelly , Dang, Alex N. , Jones, Chad H. , Pignataro, Megan E. , Graham, Justin T. , Steckelings, U. Muscha , Alexander, Jon C. , Febo, Marcelo , Krause, Eric G. , de Kloet, Annette D. , Candelario-Jalil, Eduardo and Sumners, Colin
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals. The mechanisms of this neuroprotective action are varied, and may include direct and indirect effects of AT2R activation. Our objectives were to assess...
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Full title
Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats
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Record Identifier
TN_cdi_plos_journals_1915544391
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1915544391
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0180738
