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The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependen...

The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1916991526

The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependent constitutively active and another K+-independent with essential allosteric activation

About this item

Full title

The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependent constitutively active and another K+-independent with essential allosteric activation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-07, Vol.12 (7), p.e0178673-e0178673

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In a previous phylogenetic study of the family of pyruvate kinase EC (2.7.1.40), a cluster with Glu117 and another with Lys117 were found (numbered according to the rabbit muscle enzyme). The sequences with Glu117 have been found to be K+-dependent, whereas those with Lys117 were K+-independent. Interestingly, only γ-proteobacteria exhibit sequence...

Alternative Titles

Full title

The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependent constitutively active and another K+-independent with essential allosteric activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1916991526

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1916991526

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0178673

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