Autophagy mediates cell cycle response by regulating nucleocytoplasmic transport of PAX6 in limbal s...
Autophagy mediates cell cycle response by regulating nucleocytoplasmic transport of PAX6 in limbal stem cells under ultraviolet-A stress
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Limbal stem cells (LSC) account for homeostasis and regeneration of corneal epithelium. Solar ultraviolet A (UVA) is the major source causing oxidative damage in the ocular surface. Autophagy, a lysosomal degradation mechanism, is essential for physiologic function and stress defense of stem cells. PAX6, a master transcription factor governing corn...
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Autophagy mediates cell cycle response by regulating nucleocytoplasmic transport of PAX6 in limbal stem cells under ultraviolet-A stress
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TN_cdi_plos_journals_1917696149
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1917696149
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0180868