Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B a...
Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
HLA class I glycoproteins contain the functional sites that bind peptide antigens and engage lymphocyte receptors. Recently, clinical application of sequence-based HLA typing has uncovered an unprecedented number of novel HLA class I alleles. Here we define the nature and extent of the variation in 3,489 HLA-A, 4,356 HLA-B and 3,111 HLA-C alleles....
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Full title
Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles
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TN_cdi_plos_journals_1919501467
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1919501467
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1006862
